Many people may wonder why some people get sick with diseases that their family members have never had before, or some people may be worried about whether their diseases will be passed on to future generations. Did you know that there is something that can be controlled beyond DNA that is passed down from generation to generation, namely epigenetics, that can cause changes in DNA sequences and alter gene expression? This article has the answer.

What is Epigenetics?

Epigenetics refers to the study of gene expression, where Epigenetics Reprogramming is the process of changing gene transcription patterns without changing the DNA sequence.

• DNA Methylation Methylation on DNA is one of the important epigenetics mechanisms. It affects gene expression without altering the DNA sequence. The study of DNA methylation helps to understand the mechanisms of epigenetics and the risk of developing various diseases.
• Histone Modification Histone protein is a process that affects gene expression without changing the DNA sequence, which can be associated with the development of various chronic diseases.
• MicroRNA (miRNA) Regulation is a small RNA molecule consisting of about 18-25 pairs of nucleotides. It does not translate into proteins, but rather regulates specific gene expression using miRNAs to prevent or reduce the transformation of target mRNAs, help understand the pathogenesis of the disease, and contribute to the further development of chronic disease treatments.

What behaviors do epigenetics changes occur in?

Normal cell development

Normal cell development is the process by which cells divide and grow in an orderly and normal manner, but the mechanism of epigenetics transforms two cells that divide into different types of cells and perform different functions. For example, muscle cells and neurons have the same set of DNA codes, but neurons act like electrical wires that carry nerve signals to other cells throughout the body. Muscle cells help the body move.

Aging

Epigenetics mechanisms change with age, with the mechanisms at birth being different from those in childhood and adulthood. It affects the function of cells in the body and aging.

Retreat of epigenetics mechanisms

The mechanism of change in epigenetics can be non-permanent, changing up or down depending on factors such as lifestyle and environment.

Dining

Certain types of diets, such as fruits and vegetables, vegetarian foods, or high-fat foods, can affect the mechanisms of epigenetics.

Exercise

Regular exercise Gene function can be altered through epigenetics mechanisms, as it is a behavior that helps to respond effectively to stress. Therefore, it reduces the occurrence of epigenetics mechanisms from DNA methylation and histone modification.

Examples of Adopting Gene Changes Induced by Epigenetics

Psychological disorders

Many psychological disorders, such as depression, bipolar disorder, and ADHD, are associated with epigenetics changes, with studies showing that people with depression have different patterns of DNA modifications than those who are mentally healthy.

Heart disease

Many heart diseases, such as heart attacks. Stroke and high blood pressure Epigenetics is also associated with changes in epigenetics, as studies have shown that heart attack patients have different patterns of DNA modifications than healthy people. Blood clotting and blood pressure control

Cancer

Many cancers are also associated with epigenetics changes, with studies showing that cancer cells have different patterns of DNA modification than normal cells. Cell division and cell death

However, Consultation with a qualified doctor It can reduce the impact of changes caused by epigenetics and reduce the risk of developing various diseases.

For those who are interested inIn-depth health checks at the cellular level To find out the changes caused by epigenetics, you can consult at BDMS Wellness Clinic. 02-826-9999 or LINE Official @bdmswellnessclinic